HER
Flagship Initiative

HER Science
Initiative

A women's health research and evidence programme applying a life-course approach, from adolescence to later life, to the conditions and determinants that disproportionately affect women and girls across Africa.

One approach across a woman's life

Adolescence

Menstrual health, HPV prevention, nutrition and school-age wellbeing.

Pregnancy and birth

Pregnancy, childbirth and postpartum care, including safe water and hygiene.

Midlife

Midlife transitions, early detection of cancers and chronic conditions.

Later life

Long-term health, access to care and mental wellbeing.

Research priorities

Four areas where the evidence is needed most.

We organise our work into four priority areas. Each one covers conditions that affect women across the life course, and each is shaped by local questions, local researchers and local health systems.

Where each priority is most active
SupportingCore focus
Adolescence
Pregnancy & birth
Midlife
Later life

Maternal & Reproductive Health

  • Pregnancy and postpartum complications
  • Hypertensive disorders
  • Fibroids
  • Endometriosis
  • Menstrual health
  • Midlife transitions

Women's Cancers

  • Cervical cancer
  • Breast cancer
  • HPV prevention and screening
  • Early detection
  • Equitable access to treatment

Infectious Diseases & AMR

  • HIV
  • Tuberculosis
  • Malaria
  • Neglected tropical diseases (NTDs)
  • Reproductive tract infections
  • Antimicrobial resistance

Health Systems & Determinants

  • Nutrition
  • Water, sanitation and hygiene (WASH)
  • Healthcare access
  • Mental health
  • Digital health
  • Social and structural determinants

Select a row to see the topics inside each priority. Illustrative guide to where each priority mainly applies across the life course. It shows our research focus, not measured data.

Why we created HER Science

Medicine has a history of not looking. Africa has the least evidence to fall back on.

Health research has not studied everyone equally. Women's bodies were long treated as a variation on a male standard, and research in and from Africa has received a fraction of the attention its health burden calls for. Where those two gaps overlap, African women are left with the thinnest evidence of all. This is the gap we created the HER Science Initiative to close.

Antiquity to the 19th century

Pain without a name

What was missed

Almost any unexplained symptom in a woman, from pelvic pain to seizures, could be filed under "hysteria". Distinct chronic conditions went unrecognised and unstudied.

What it cost

Women living with conditions we now recognise, such as endometriosis, epilepsy or depression, were dismissed, isolated or institutionalised, and their suffering left no scientific record.

1970s to 1980s

The data desert

What was missed

Women of childbearing age were largely kept out of early-phase drug trials. Hormones, body weight and metabolism were rarely studied, and medicines were dosed to a male standard.

What it cost

Women experience more adverse drug reactions than men. Several widely used medicines reached the market with little data on how they behave in female bodies.

The 1990s

The male default

What was missed

Even after women entered trials, results were often pooled, which hid differences between the sexes. Heart research treated the male pattern of heart attack as the standard.

What it cost

Women with atypical symptoms such as nausea, jaw pain or deep fatigue were more likely to be misdiagnosed and sent home. Heart disease remains a leading cause of death for women.

2000s to today

The cell-level omission

What was missed

For decades, much laboratory science relied on male animals and male cell lines. Female biology was left out at the earliest stage of discovery.

What it cost

Women make up around 80% of people with autoimmune disease, yet diagnosis can take years and many doctors. Delays of 7 to 10 years are widely reported for endometriosis.

The African gap

Where the evidence is thinnest, the burden is heaviest.

What was missed

Most of the evidence used to guide care was generated elsewhere, in populations, health systems and living conditions that differ from those across Africa. Africa-specific, sex-disaggregated data on women's health is still scarce, and that scarcity is itself the gap.

What it cost

Clinicians and policymakers are left to apply findings that may not fit, and African women carry the cost of questions that were never asked locally. Researchers on the continent often lack funding, mentorship and pathways to turn their work into policy.

~70%of the world's maternal deaths in 2023 occurred in sub-Saharan Africa (WHO)
~20-25%of the global disease burden is in Africa, by commonly cited estimates
~1-3%of global research output comes from Africa, by commonly cited estimates

So we created HER Science to change who asks the questions about women's health.

With the Initiative, we build the pathway that is missing for women's health: African researchers generating locally relevant evidence, early-career talent mentored to lead it, and findings explained clearly enough for communities, practitioners and policymakers to use.

  • Generate evidence from African populations
  • Develop researchers who stay and lead
  • Translate findings into plain language
  • Solve with communities and policymakers

Historical and global figures are widely cited in the medical literature and are summarised here for context, not as new findings. Regional figures are approximate and vary by source and year. Maternal mortality: WHO / UN Maternal Mortality Estimation Inter-Agency Group, 2023 estimates, published 2025.

Be part of the research network.

Researchers, institutions and partners are welcome to join the HER Science Initiative.

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